Recently, Bischoff et al. has described the synthesis of 2,3-Dihydropyrrolopyridinone by a tandem aminomethylation-Cyclization using in situ generated formimine and an ortho-lithiated pyridinecarboxamide, depending on the reaction conditions it is also possible to continue the cascade reaction with a bis alkylation of the pyrrolidinone ring.
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2 commentaires:
Dear Hetchem,
I enjoy your blog, but are you still alive ? No more news since one month !
Yours,
A chemist.
pourquoi pas:)
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